CVE-2025-12921

OpenClinica Community Edition CRF Data Import ImportCRFData xml injection

CVSS 5.3 MEDIUMEPSS 0.5%CWE-74 CWE-91

Vexday Risk Score

13Low

SSVC decision (CISA)

Track

No exploitation signal → monitor

CVSS 5.3EPSS 0.5%KEV nãoPoC —Patch —

Lifecycle

Nov 09, 2025Published on NVD

Recommendation: Monitor — no exploitation signal at the moment.

A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way.

CVSS:4.0/AV:N/AC:L/AT:N/PR:L/UI:N/VC:L/VI:N/VA:N/SC:N/SI:N/SA:N/E:P

Affected products

OpenClinica · Community Edition

Want to know if your infrastructure is exposed to this?

Talk to TrueHacking →

References

https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md#poc https://vuldb.com/?ctiid.331641 https://vuldb.com/?id.331641 https://vuldb.com/?submit.680872